Kenneth Mark, MD, a dermatologist in NYC and clinical professor of dermatology at NYU, is one of the first in NYC to offer the recently-launched Neubelle treatment and says he's been blown away by the results. "It provides similar effects to Botox but using a different mechanism," explains Dr. Mark. "Botox uses a toxin to block the release of a neurotransmitter, so the muscle is inhibited. Neubelle creates a small thermal injury the size of a grain of rice, which serves as a roadblock for the nerve to conduct to the muscle."
Although it uses an alternative path to gain similar Botox-like results, what is the same—it requires needles and may cause some uncomfortable pain, too (so needle phobes, do not rejoice). First, instead of numbing cream, skin is prepped with numbing injections. Next, a doctor stimulates the muscle that needs to be treated in order to target specific placement (giving it a little shock to see it contract), then uses the tiny probe to create the thermal injury. Another advantage of Neubelle, according to Dr. Mark: unlike Botox which floods the entire area once injected, using Neubelle's teeny probe to single out a specific nerve, allows a doctor to "really focus on the exact nerve that you want to block" for wrinkle-smoothing customization. Then there's the fact that it could be a solution for the Botox resistant, as in after years of use, the neurotoxin doesn't take well for them anymore.  
Another thing to consider—where you want to erase wrinkles matters. Unlike Botox, Neubelle can only be used on the forehead (not around the eyes, too). And one session is way higher than the going rate for Botox—depending on where you are in the country, it could cost about $3,000. But Dr. Mark, says that price could be well worth it. "Results are immediate, and should last at least eight months but could last a year or longer—in some cases, up to two years is possible," he says.